Free Serum Vitamin B12 Level in Certain Hematologic Disorders
نویسندگان
چکیده
منابع مشابه
Free serum vitamin B12 level in certain hematologic disorders.
IN NORMAL HUMAN SERUM, vitamin B12 exists mainly as a heat-labile complex bound to alpha-i globulin. A small fraction is present free or uncombined. Total vitamin B12 content of serum represents the sum of free and bound forms. These fractions are estimable with microbiologic methods. \licrobiologic assay of vitamin B12 in serum is now recognized to be one of the standard methods for proper app...
متن کاملHematologic responses and concentration of vitamin B12 in serum and urine following oral administration of vitamin B12 without intrinsic factor.
By G. I. M. Ross, M.B., Cri.B. D.C.P.,* D. L. MOLLIN, B.SC., M.B., Cnl.B., E. V. Cox, B.Sc., M.B., B.S., AND C. C. TJNGLEY, M.D., M.R.C.P.* T LIE ABSORPTIOX from the imnt.cstinal tract of small doses of n-itaminn B,2 is impaired inn paticnnts with pernicious anemia. Small doses such as 5 g. gin-cnn daily by mouth produce little or rio hematologic respomise, unnless gin-cnn ssit.in a source of i...
متن کاملThe Value of the Serum Vitamin B12 Level in Diagnosing B12 Deficiency
Serum vitamin B,2 levels of 2523 individuals were measured using the hemoglobin-coated charcoal assay. In one hespital, the test was performed on 1698 patients under hematologic evaluation for erythrocytic abnormalities of all types, while 825 patients from five other hospitals were studied because of suspected B,2 deficiency. The incidence of low serum vitamin B,2 was surprisingly low for both...
متن کاملThe value of the serum vitamin B12 level in diagnosing B12 deficiency.
Serum vitamin B,2 levels of 2523 individuals were measured using the hemoglobin-coated charcoal assay. In one hespital, the test was performed on 1698 patients under hematologic evaluation for erythrocytic abnormalities of all types, while 825 patients from five other hospitals were studied because of suspected B,2 deficiency. The incidence of low serum vitamin B,2 was surprisingly low for both...
متن کاملThe Value of the Serum Vitamin B12 Level in Diagnosing B12 Deficiency
Serum vitamin B,2 levels of 2523 individuals were measured using the hemoglobin-coated charcoal assay. In one hespital, the test was performed on 1698 patients under hematologic evaluation for erythrocytic abnormalities of all types, while 825 patients from five other hospitals were studied because of suspected B,2 deficiency. The incidence of low serum vitamin B,2 was surprisingly low for both...
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ژورنال
عنوان ژورنال: Blood
سال: 1960
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v15.5.630.630